Genetic characterization of the mRNAs encoding alpha-bungarotoxin: isoforms and RNA editing in Bungarus multicinctus gland cells

A cDNA sequence encoding a neurotoxin-homolog from Bungarus multicinctus.

The venoms of both Elapidae and Hydrophiidae are mixtures of proteins some of which are blockers of the rucotinic acetylcholine receptor (1). They are classified into shortneurotoxins (60 to 62 residues), long-neurotoxins (70 to 74 residues) and x-neurotoxins (66 residues) (2). Some peptides are classified as neurotoxin-homologs with unknown pharmacological activity (1). Here we present the fir...

Effectiveness of Alpha Chymotrypsin on the Treatment of Severe Paralysis due to Bungarus Multicinctus Snakebite

Recognition of Bungarus multicinctus Venom by a DNA Aptamer against β-Bungarotoxin

Antibody-based technology is the main method for diagnosis and treatment of snake bite envenoming currently. However, the development of an antibody, polyclonal or monoclonal, is a complicated and costly procedure. Aptamers are single stranded oligonucleotides that recognize specific targets such as proteins and have shown great potential over the years as diagnostic and therapeutic agents. In ...

phylogeography and genetic diversity of the lesser mouse- eared bat (myotis blythii) in iran

in current study, 63 samples of bat populations collected from differ regions were used for evaluating the geographic variations. twenty cranial and dental characters for traditional morphometric and landmarks method on the ventral, dorsal skull and mandible for geometry morphometric studies were used. statistical analyses of traditional morphometric and geometry morphometric data indicated low...

Production and Characterization of Neutralizing Antibodies against Bungarus multicinctus Snake Venom

The venom of the banded krait (Bungarus multicinctus), one of the major venomous species in Taiwan, contains neurotoxic venom proteins (B. multicinctus proteins) that pose a serious medical problem in tropical and subtropical countries. Even though horse-derived serum is an efficient therapy against snake venom, it is associated with a high cost and side effects. Therefore, developing a more co...